Nu-Derm
Condition & Enhance
Obagi C-Rx
Pro-C Serums
ELASTIderm Eye Treatment
ELASTIderm Decolletage
CLENZIderm M.D.
Rosaclear
Nu-DermCondition & EnhanceObagi C-RxPro-C SerumsELASTIderm Eye TreatmentELASTIderm DecolletageCLENZIderm M.D.Rosaclear

Nu-Derm® System

Over the years, your skin has been exposed to a number of environmental stressors, which cause damage that can reach the deepest layers of your skin. Photodamage, caused by the sun's harmful rays, is the main cause of the fine lines, wrinkles and age spots that you may already see or you will eventually see on your face.

The Nu-Derm System is the physician-dispensed, prescription-strength skin care system that can actually transform your skin at the cellular level. By addressing the signs of photodamage and restoring the healthy function of your skin cells, this system is clinically proven to result in younger- and healthier-looking skin.

How it works

What are the effects of photodamage on your skin?

As your skin ages and is exposed to UVA and UVB rays, the turnover of skin cells slows significantly, throwing off the balance between the growth of healthy new cells and the sloughing of old, damaged cells. Additionally, collagen and elastin begin to break down, causing the skin to lose resilience resulting in fine lines, wrinkles and sagging. Daily exposure to UV light then accelerates this aging process and may cause uneven coloring.

See how it works

Signs of photodamage and aging

  • Age spots
  • Fine lines and wrinkles
  • Rough skin
  • Skin laxity
  • Erythema (Redness)
  • Sallowness (Complexion)
  • Hyperpigmentation (Discoloration)

How does the Nu-Derm System transform your skin?

The Nu-Derm System penetrates below the surface of your skin to transform skin cell functions at the cellular level and correct the damage within.

Using a specific dose and frequency that's recommended specifically by your skin care professional for your skin condition, the prescription-strength system exfoliates old skin leaving healthy, new skin that looks and acts younger and healthier.

Glowing praise from users

The Obagi Nu-Derm System receives glowing reviews from users. Read what they have to say about their experiences and radiant results.


We have used the Obagi Nu-Derm skin care system for 17 years and I have not found any other system that is comparable to the excellent results for rejuvenating and maintaining healthy skin for all skin types and conditions.
Jody Comstock, M.D.
Founder/Physician,
Skin Spectrum, Tuscon, AZ

I started the Obagi [Nu-Derm] System about 2 weeks ago to improve melasma on my face after my dermatologist recommended that I try it.

WOW! In only two weeks, most of my melasma has improved and the really tough spots I've had for years are noticeably faded! I am so delighted with your product! Even the redness and peeling (which I was warned ahead of time would happen) were very manageable.

Some women in my office approached me the other day to ask what I was doing to my skin because it looked so smooth and radiant. I was floored! Again, thank you.

Christine W.
Bedford, NH
I purchased Obagi [Nu-Derm System] and it is wonderful. For the first time in my entire life, I am happy with my skin. I never have been before, as I've had acne and blotchy skin for so long. It's only been about 3 weeks, but I wanted you to know how happy I am with these products. Thank you.
Stephanie R.,
Vacaville, CA
Thanks to such a great skin care system [Obagi Nu-Derm], my acne scars have diminished to the level I couldn't have even imagined or hoped for with skin care. My skin is more even toned and my ice pick scars are now very shallow. I'm no longer a targeted customer at the cosmetic counter. Some of my friends and family are so amazed that they have [also] gone on Obagi [Nu-Derm].
T.K,
New York, NY
I really didn't like the texture of my skin, my pore size and I had a lot of hyperpigmentation. I was a little intimidated to have to use so many products and have to buy into some sort of system. I was skeptical. But all I can say is WOW! What a transformation.
Paige,
Orinda, CA

Who should use the Nu-Derm System?

If you've experienced occasional sunburns, daily sun exposure, hormonal changes, stress and environmental pollution, then your skin will likely show signs of premature aging or occasional acne flares.Your genetic history may also make you more prone to the effects of aging skin. Talk with your skin care professional about how the Nu-Derm System can be tailored to your skin care goals and your skin type.


Before

After 12 weeks 

Before

After 12 weeks

The Obagi Nu-Derm System has helped users transform their skin at the cellular level so that it looks and acts younger and healthier. These before and after photos are just some of the results from Obagi Nu-Derm users.

Frequently asked questions

How quickly will I see results when using the Nu-Derm System?
Your individual prescribed protocol and frequency of use should be determined by your skin care professional, but you can typically expect visible improvements in four to six weeks.
What can I expect while using the Nu-Derm System?
You will likely experience four phases of transformation. For special tips on what to expect during the transformation process, click here.
Why is the Nu-Derm System sold exclusively by physicians?
The Nu-Derm System contains prescription-strength formulations that can only be sold through a licensed physician, such as a dermatologist or plastic surgeon.
What is the difference between the Nu-Derm System and products purchased from department stores, drug stores and infomercials, etc?
The products in the Nu-Derm System are clinically proven, prescription-strength, ingredients that work at the cellular level to improve your skin cell function. Products purchased from a retail store are cosmetic-based products that do not contain prescription-strength ingredients.
How often should I visit my dermatologist, plastic surgeon or other skin care professional when using the Nu-Derm System?
Your dermatologist or plastic surgeon will talk with you about how often you should check in once you've started using the Nu-Derm System.
Can the Nu-Derm System be used during pregnancy?
Please consult your physician and refer to Important Product Information by clicking here.
Can the Nu-Derm System be used if I will be in the sun (i.e. at sporting events or at the beach)?
Keeping in mind that extended sun exposure damages the skin, it is suggested that you avoid prolonged sun exposure without protection. While on the system, you can participate in normal outdoor activity, however, your skin may be sensitive to the sun and heat. It is very important to always wear a sunscreen, like the Healthy Skin Protection SPF 35 and/or the Physical UV Block SPF 32 in the Nu-Derm System, and reapply sun protection every few hours while exposed to the sun.
Why should I use all the products in the Nu-Derm System?
Each product in the Nu-Derm System is specifically designed to work together to provide you with the best results. When used as a system, the prescription-strength ingredients work to effectively balance the pH level of your skin and penetrate into the layers of your skin for superior results. Your skin care professional will guide you in using the system based on their assessment of your needs.

Clinical evidence

Regardless of skin type and condition, the Nu-Derm System has repeatedly demonstrated clinically-significant results. In a recent clinical study involving 301 patients, the Nu-Derm System showed 2-3 times greater improvement than other commonly used stand alone treatments.*

In only 12 weeks, patients with mild to moderate photodamaged skin enjoyed greater improvements in key measures of photodamage, including wrinkles, firmness and hyperpigmentation.


Before

After

The Nu-Derm System is clinically proven to have...

  • 3x greater improvement in reducing mottled hyperpigmentation and sallowness than a hydroquinone treatment
  • 6x greater improvement in reducing fine lines and wrinkles than the most commonly recommended over-the counter skin care products

*Published in Cosmetic Dermatology, April, 2006.

Protocol for use

The Obagi Nu-Derm System offers a complete, convenient protocol for treatment at home. Below is a standard protocol for how the products in the system are used. Your Physician and Skin Care Specialist will design a specific protocol that incorporates dosing, frequency and treatment objectives for your skin.

Printable version

Morning Routine
PREPARE
STEP 1
Obagi Nu-Derm Gentle Cleanser or Foaming Gel
Wash your face with the recommended cleanser, rinse with lukewarm water and gently pat dry. Avoid rubbing your skin with a towel.
STEP 2
Obagi Nu-Derm Toner
Put the Toner on a cotton pad and apply to your entire face. Do not rinse.
CORRECT
STEP 3
Obagi Nu-Derm Clear
Measure 1/2 -1 gram and apply evenly to your entire face, avoiding the eyes, extending to the hairline, over the ears and ending with a feathering motion.

Note: If you have dark skin, use Clear on your entire face once a day, preferably in the morning, and apply at night only on the darkest areas. Once you achieve satisfying results, use Clear only as needed.
STEP 4
Obagi Nu-Derm Exfoderm or Exfoderm Forte
Measure 1/2 -1 gram and apply evenly to your entire face, avoiding the eyelid area. Massage until the cream is completely absorbed.
PROTECT
STEP 5
Obagi Nu-Derm Healthy Skin Protection SPF 35
Apply in the morning under your makeup. Reapply often while in the sun. Note: Always avoid prolonged direct sun exposure. Remember to practice sun protection daily.
Evening Routine
PREPARE
STEP 1
Obagi Nu-Derm Gentle Cleanser or Foaming Gel
Wash your face with the recommended cleanser, rinse with lukewarm water and gently pat dry. Avoid rubbing your skin with a towel.
STEP 2
Obagi Nu-Derm Toner
Put the Toner on a cotton pad and apply to your entire face. Do not rinse.
CORRECT
STEP 3
Obagi Nu-Derm Clear
Measure 1/2 -1 gram and apply evenly to your entire face, avoiding the eyes, extending to the hairline, over the ears and ending with a feathering motion.

Note: If you have dark skin, use Clear on your entire face once a day, preferably in the morning, and apply at night only on the darkest areas. Once you achieve satisfying results, use Clear only as needed.
STIMULATE
STEP 4
Obagi Nu-Derm Blender
Measure 1/2 gram of Blender—As directed by your physician, apply Blender and Tretinoin evenly to your entire face. Apply around eye area as directed.

Note: Avoid the corners of the lips and creases around the nose.
Obagi Tretinoin
As prescribed by your physician

Using the Obagi Nu-Derm System

The Obagi Nu-Derm products are designed in a system with a specific dosage and frequency to maximize your results.

View Nu-Derm Prescribing Information
View Tretinoin Prescribing Information

  • Prepare
  • Improve
  • Stimulate
  • Protect
  • Compliment
  • As Prescribed
Obagi Nu-Derm Foaming Gel (1) - For Normal/Oily Skin
Obagi Nu-Derm Foaming Gel (1) - For Normal/Oily Skin
A gel-based cleanser that removes impurities, oil and make-up to leave even the oiliest skin clean and fresh.
Obagi Nu-Derm Gentle Cleanser (1) - For Normal/Dry Skin
Obagi Nu-Derm Gentle Cleanser (1) - For Normal/Dry Skin
A mild gel-based cleanser that gently removes impurities, oil and makeup to leave skin clean and fresh.
Obagi Nu-Derm Toner (2)
Obagi Nu-Derm Toner (2)
Adjusts the pH of the skin for increased penetration of the system ingredients.
Obagi Nu-Derm Clear (3)
Obagi Nu-Derm Clear (3)
A topical prescription treatment that includes 4% hydroquinone to correct hyperpigmentation (discoloration) and improve and even skin tone.
Obagi Nu-Derm Exfoderm® Forte (4) - For Normal/Oily Skin
Obagi Nu-Derm Exfoderm® Forte (4) - For Normal/Oily Skin
An alpha hydroxy acid (6% glycolic acid, 4% lactic acid) that removes old skin cells while promoting new skin cells for a lighter, brighter, firmer complexion for skin that needs deeper exfoliation.
Obagi Nu-Derm Exfoderm (4) - For Normal/Dry Skin
Obagi Nu-Derm Exfoderm (4) - For Normal/Dry Skin
A plant acid (3% phytic acid) that removes old skin cells while promoting new skin cells for a lighter, brighter complexion.
Obagi Nu-Derm Blender® (5)
Obagi Nu-Derm Blender® (5)
A topical prescription treatment that contains 4% hydroquinone to target hyperpigmented (discolored) areas of the skin and increase the penetration of the active ingredients of the system.
Tretinoin Cream 0.025%, .05% and .1% (as prescribed)
Tretinoin Cream 0.025%, .05% and .1% (as prescribed)
A topical prescription for the treatment of acne. Use as directed by your skin care professional.
Click here to download the product information sheet.
Obagi Nu-Derm Healthy Skin Protection SPF 35 (6)
Obagi Nu-Derm Healthy Skin Protection SPF 35 (6)
A sunscreen with 9% micronized zinc oxide and 7.5% octinoxate that helps to protect newly transformed, younger looking skin.
Obagi Nu-Derm Sunfader SPF 15 (6)
Obagi Nu-Derm Sunfader SPF 15 (6)
A topical prescription treatment that helps to protect skin from ultraviolet damage with 7.5% octinoxate and 5.5% oxybenzone, while correcting uneven surface skin color and brown spots with 4% hydroquinone 2.0 fl oz (57 g)
Obagi Nu-Derm Physical UV Block SPF 32 (6)
Obagi Nu-Derm Physical UV Block SPF 32 (6)
A sunscreen with 18.5% Zinc Oxide that helps to protect the newer, healthier skin created by your skin transformation 2.0 oz (57 g)
Obagi Nu-Derm Eye Cream
Obagi Nu-Derm Eye Cream
A light moisturizing cream specially formulated to help control dryness around the sensitive eye area. 0.5 fl oz (15 ml)
Obagi Nu-Derm Tolereen
Obagi Nu-Derm Tolereen
Contains 0.5% hydrocortisone for the temporary relief of itching and burning associated with minor skin irritations. 2.0 oz (57 g)
Obagi Nu-Derm Action
Obagi Nu-Derm Action
A moisturizing cream to be used as needed to soothe areas of dry, flaky skin. 2.0 oz (57 g)